Advanced Osteoarthritis Therapeutics

Revolutionary nanotechnology platform delivering targeted joint pain relief, cartilage protection, and disease modification for comprehensive osteoarthritis management

75% Joint Pain Reduction
60% Improved Mobility
50% Cartilage Protection
32M US Adults with OA

Comprehensive OA Treatment Solutions

Multi-modal nanotechnology platform addressing pain, inflammation, and disease progression in osteoarthritis

Targeted Topical Nano-Gels

Advanced topical formulations with deep joint penetration for localized osteoarthritis pain and inflammation management.

  • Deep synovial fluid penetration
  • Sustained 12-hour relief
  • No systemic absorption
  • Joint-specific targeting
  • Compatible with existing therapies
Pre-Clinical Development

Intra-Articular Injections

Direct joint injection therapy with enhanced bioavailability and extended duration for severe OA cases.

  • Direct joint cavity delivery
  • Extended 3-month duration
  • Cartilage protective effects
  • Reduced injection frequency
  • Superior to hyaluronic acid
Preclinical Studies

Disease-Modifying Therapy

Breakthrough formulations targeting cartilage degradation and promoting joint health preservation.

  • Cartilage matrix protection
  • Chondrocyte preservation
  • Inflammatory cascade interruption
  • Joint space preservation
  • Long-term disease modification
Research Phase

Mobility Enhancement Protocol

Integrated treatment approach combining pain relief with functional improvement and quality of life enhancement.

  • Functional mobility improvement
  • Range of motion enhancement
  • Activity level restoration
  • Quality of life improvement
  • Exercise tolerance increase
Development Phase

Comprehensive Joint Health Management

Complete care pathway from early intervention to advanced disease management

Early Detection & Prevention

Proactive intervention strategies for patients at risk of developing osteoarthritis or showing early symptoms.

  • Risk factor assessment
  • Early biomarker detection
  • Preventive therapy initiation
  • Lifestyle modification support

Mild to Moderate OA

Targeted treatment for patients experiencing joint pain and early functional limitations with minimal cartilage damage.

  • Topical nano-gel therapy
  • Pain and inflammation control
  • Mobility preservation
  • Disease progression prevention

Severe OA Management

Advanced interventions for patients with significant joint damage, severe pain, and functional impairment.

  • Intra-articular injections
  • Comprehensive pain management
  • Functional restoration
  • Pre-surgical optimization

Long-term Wellness

Ongoing support and maintenance therapy to preserve joint health and maintain quality of life over time.

  • Disease modification protocols
  • Long-term joint preservation
  • Quality of life maintenance
  • Integrated care coordination

Advanced Mechanism of Action

Our nanotechnology platform delivers salsalate directly to affected joint tissues, targeting multiple pathways involved in osteoarthritis pathogenesis and progression.

The nanoformulated approach enables precise targeting of inflammatory mediators, cartilage-degrading enzymes, and pain pathways while protecting healthy joint structures.

This multi-target strategy addresses both symptoms and underlying disease mechanisms, offering comprehensive osteoarthritis management beyond traditional approaches.

Anti-Inflammatory

Targeted reduction of pro-inflammatory cytokines and mediators

Cartilage Protection

Prevention of matrix metalloproteinase-mediated cartilage degradation

Pain Modulation

Direct inhibition of pain signaling pathways in joint tissues

Tissue Repair

Promotion of chondrocyte survival and matrix synthesis

Measurable Patient Impact

Significant improvements in pain, function, and quality of life for osteoarthritis patients

75%
Pain Score Improvement

Significant reduction in WOMAC pain scores and daily discomfort levels

60%
Mobility Enhancement

Improved walking distance, stair climbing, and activities of daily living

50%
Cartilage Preservation

Reduced cartilage loss and joint space narrowing progression

80%
Treatment Satisfaction

High patient satisfaction with symptom relief and functional improvement

45%
Reduced Medication Use

Decreased reliance on NSAIDs and other systemic pain medications

32M
Potential US Patients

Americans diagnosed with osteoarthritis who could benefit from treatment

Advance Osteoarthritis Care

Partner with us to bring breakthrough osteoarthritis treatments to patients. Join leading rheumatologists and orthopedic specialists in transforming joint health through innovative nanotechnology.